Doctor Experiences

Clinical experiences of doctors who have treated their patients with phage therapy

Dr. Mahendra Kumar Sharma
Senior Consultant Urologist
Yatharth Hospital, Noida, UP
My clinical experience of phage therapy showed significant effectiveness in 15 patients with prostatitis. Patients received phages orally, intravesically or per rectally. Clinical effectiveness observed by doing two DRE (Digital Rectal Examination) and EPS (Expressed Prostatic Secretion) cultures post phage therapy.
 
The following were the findings observed after phage therapy:
  1. Significant reduction in prostate tenderness or size
  2. Significant reduction in EPS volume
  3. Reduction in EPS leukocyte counts
  4. Increase in maximum urine flow
  5. Reduction in Dysuria / frequency of urination
  6. No significant side effects
Dr. Sony Mehta
Consultant Urologist
Hinduja Hospital, Mumbai

My experience of phage therapy is with 3 patients presenting with prostatitis, urethritis and UTI.

Given here is the case presentation of the clinical summary of my first patient treated with phage therapy:

  • 42 year old male, presented with typical symptoms of prostatitis and urethritis.
  • Patient was treated with multiple antibiotics. His symptoms showed partial improvements, with relapse within few weeks of completing course. The side effects from the multiple antibiotics courses were intolerable.
  • Patient was then suggested phage therapy. We followed the prescription from the urologist at the Eliava clinic. Phages were delivered rectally, orally and via urethral instillation. Patient was quickly into remission with many symptoms resolving over 3 months.
Dr. Vijil Rahulan
Chief, Transplant Pulmonology
KIMS Hospital, Hyderabad

We have used phages in our post Bilateral Lung Transplantation patient with chronic MDR Pseudomonas airway colonisation leading to recurrent airway narrowing and cough.

Phages were given orally and in nebulization form.

Use of phages decreased bacterial colony count in BAL, decreased the frequency of airway narrowing therefore improving FeV1, 6 minutes walk distance and functional capacity.

We haven’t see any complications during course of therapy.

Dr. Mayank Jain
Consultant, Urology
Fortis Escorts Hospital, Delhi

I was associated with Vitalis Phage Therapy and Dr Dangs Lab for two years for consulting and conducting testing for chronic prostatitis patients opting for phage therapy between 2023 and 2025.

Chronic prostatitis patients had already taken multiple course of antibiotics with only partial relief and significant side effects.

Over 100 patients of chronic prostatitis used oral, intravesical and rectal phages.

Follow up EPS volume and white blood cell count improved in >75% patients, and most of them had near complete resolution of their pelvic pain and significant reduction in LUTS, without any side effects of phage therapy.

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